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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA3
All Species:
31.82
Human Site:
S456
Identified Species:
70
UniProt:
P51812
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51812
NP_004577.1
740
83736
S456
A
V
K
I
I
D
K
S
K
R
D
P
T
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104305
745
83841
S460
A
V
K
I
I
D
K
S
K
R
D
P
S
E
E
Dog
Lupus familis
XP_548888
711
80690
S427
A
V
K
I
I
D
K
S
K
R
D
P
T
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P18654
740
83675
S456
A
V
K
I
I
D
K
S
K
R
D
P
T
E
E
Rat
Rattus norvegicus
Q63531
735
82865
S452
A
V
K
V
I
D
K
S
K
R
D
P
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513942
700
79225
D419
I
I
D
K
S
K
R
D
P
T
E
E
I
E
I
Chicken
Gallus gallus
P18652
752
84421
S469
A
V
K
V
I
D
K
S
K
R
D
P
S
E
E
Frog
Xenopus laevis
P10665
733
82620
T450
A
V
K
V
I
D
K
T
K
R
D
P
S
E
E
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
S454
A
V
K
I
I
D
K
S
K
R
D
P
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
F659
K
I
I
P
L
S
K
F
R
P
S
E
V
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
A492
V
K
K
A
V
F
D
A
T
E
E
V
D
I
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.7
94.5
N.A.
99.8
80.8
N.A.
93.2
80.1
77.4
82
N.A.
24.3
N.A.
57.6
N.A.
Protein Similarity:
100
N.A.
86.3
95.2
N.A.
99.8
88.6
N.A.
94.1
87.5
86
89.3
N.A.
37.2
N.A.
71.5
N.A.
P-Site Identity:
100
N.A.
93.3
100
N.A.
100
86.6
N.A.
6.6
86.6
80
93.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
73
10
10
0
0
73
0
10
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
19
19
0
82
73
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
19
10
46
73
0
0
0
0
0
0
0
10
10
10
% I
% Lys:
10
10
82
10
0
10
82
0
73
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
10
10
0
73
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
73
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
0
64
0
0
10
0
46
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
10
0
0
28
0
0
% T
% Val:
10
73
0
28
10
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _